MAFUSOL ^®
(Potassium Chloride + Magnesium Chloride + Sodium Chloride + Sodium Fumarate)

Pharmacological properties. Combination drug acting as anti-oxidant, rehydrating, antiaggregant, diuretic and detoxifying agent. Activates adaptation of the cells to oxygen deficiency; quickly replenishes circulating blood volume in hypovolemic states, prevents tissue dehydration, reduces blood viscosity, improves its rheological properties, demonstrates hemodynamic effect.

Indications. Hypovolemia and hypoxia (blood loss, shock, trauma, poisoning). Acute cerebrovascular events of ischemic and hemorrhagic type in adults. As a perfusion component to fill the circuit of the artificial blood-circulation apparatus in cardiac surgery in adults and children.

Dosage and Administration. Mafusol is administered intravenously or intra-arterially. The dose and rate of the drug infusion are selected according to the indication and condition of the patient. In mild or moderate shock in adults (haemorrhagic, burn, traumatic, operative) Mafusol is administered at a dose of 2-3 liters, initially by bolus infusion, and when hemodynamic parameters are normalized — by IV drip; in children at a dose of 20-25 ml/kg.

It is recommended to use Mafusol in combination with erythrocyte-containing media as well as colloid haemodynamic blood substitutes for severe shock in adults. Mafulsol dose in this case is selected individually, but not less than 1 litre; children are administered at least 15 ml/kg. In severe intoxications in adults (peritonitis, septicaemia, intestinal obstruction, etc.) infuse up to 2-3 litres/day in combination with other detoxifying agents; in children —at a dose of 30-35 ml/kg/day.